NOT KNOWN FACTS ABOUT GR

Just one nucleotide polymorphism that replaces A with G in the nucleoside 3669 (A3669G) located in The three’ end of exon 9b has long been described in a European inhabitants (461). This polymorphism will not change the amino acid sequence but boosts the balance of GRb mRNA and boosts GRb protein expression, leading to bigger inhibition of GRa-in